Step 1. Associate each label below with the correct image to Indicate whether It relates to Intramembranous ossification or endochondral ossification. Intramembranous ossificalion Ossification of hyaline cartilage Maxilla Parietal bones Metaphyses Skipped Primary and secondary marrow cavities Endochondral ossification Femur Bony collar ...simple process of bone formation used in flat bones. STEP 1 of intramembranous ossification. DEVELOPMENT OF OSSIFICATION CENTER. - cluster of cells develop into ossification center. - osteoblasts secrete extracellular matrix. 3 MULTIPLE CHOICE OPTIONS. STEP 1 of intramembranous ossification.Put the steps of endochondral ossification in the correct order: - blood vessels and differentiating osteoblasts from periosteum invade the disintegrating tissue. - osteoblasts …Dec 28, 2020 · The initial phase of regeneration involves the repair of the pedicle following loss of the previous year's antler and is via intramembranous ossification. 351 Once this pedicle repair has been completed, the new antler proper is produced by endochondral ossification from the periosteal cells of the pedicle, a highly proliferative layer with the ... Osteon (Haversian system) consists of central canal, lamellae (rings), lacunae, osteocytes and canaliculi. The structural unit of compact bone is the osteon, an elongated cylinder oriented parallel to the long axis of the bone. Bones are covered and lined by a protective tissue called periosteum. The inner (osteogenic) layer consists primarily ...Anatomy and Physiology questions and answers. Endochondral Ossification Correctly sequence the steps of endochondral ossification. Osteoblasts beneath the periosteum deposit a thin layer of compact bone. Cartilage tissue breaks down while the periosteum develops Blood vessels and osteoblasts from the penosteum invade the disintegrating …Intramembranous ossification is the process of bone development from fibrous membranes. It is involved in the formation of the flat bones of the skull, the mandible, and the clavicles. Ossification begins as mesenchymal cells form a template of the future bone. Osteogenic cells. Osteogenic cells become osteoblast.Anatomy and Physiology questions and answers. Place the events of intramembranous ossification in the order in which they occur. 1. Development of an ossification center inside of the fibrous membrane (mesenchyme). 2. Mesenchymal cells differentiate and the periosteum is formed. 3. Bone matrix secreted osteoblast forming early spongy bone.Correctly order the following key steps in the process of endochondral ossification. 1. Chondrocytes die. 2. Osteoblasts build the bone collar on the external surface of the bone. 3. Perichondrium is invaded by blood vessels. 4. In the primary ossification center, osteoblasts replace calcified cartilage with early spongy bone. 5.Discover the intramembranous ossification steps, the cells involved in the process, and what differentiates intramembranous ossification from endochondral …Study with Quizlet and memorize flashcards containing terms like Which of of the following selections correctly lists the sequence of events that occur during intramembranous ossification?, Calcium is involved in all of the following important bodily functions except, The general process by which bones form is called and more.Intramembranous ossification of non-vault bones (e.g., bones of the facial skeleton) is not well described. ... Remodeling of the bony region is the last step in the process. Open in a separate window. Figure 4. Schematic of the cellular zones of distraction osteogenesis. The fibrous interzone (FIZ) forms first and is composed of a variety of ...[1] Light micrograph of a nidus consisting of osteoprogenitor cells that are displaying a prominent Golgi apparatus. The process of intramembranous ossification starts when a small group of adjacent MSCs begin to …Cell biology. endochondral bone formation occurs with a cartilage model. chondrocytes produce cartilage which is absorbed by osteoclasts. osteoblasts lay down bone on cartilaginous framework (bone replaces cartilage, cartilage is not converted to bone) forms primary trabecular bone. bone deposition occurs on metaphyseal side. Intramembranous ossification. 1. Begins when some of the mesenchymal cells in the membrane become osteochondral progenitor cells, which specialize to become osteoblasts. The osteoblasts produce bone matrix that surrounds the collagen fibers of the C.T. membrane, and the osteoblasts become osteocytes. As a result of this process, many tiny ... Terms in this set (5) step 1. mesenchymal cells cluster and differentiate into osteoblasts. secrete bone matrix components that crystallize with calcium salts. step 2. some osteoblasts are trapped in the bone matrix and differentiate into osteocytes. bone grows spicules outward from ossification centers. step 3.Intramembranous ossification. Intramembranous ossification forms flat and irregular bones. In this process, mesenchymal cells differentiate directly into osteoblasts; specialized cells that secrete bone matrix. As the osteoblasts are housed within the matrix they secrete, they become progressively distanced from each other but remain connected ...Isolated lissencephaly sequence (ILS) is a condition that affects brain development before birth. Explore symptoms, inheritance, genetics of this condition. Isolated lissencephaly ... Answer and Explanation: 1. Most bones in the human body originate from hyaline cartilage in a process known as endochondral ossification. This process, reflected in the development of the femur in figure 1 below, occurs in the following sequence: Chondrocytes in the center of the shaft of cartilage enlarge such that the extracellular matrix is ... Anatomy and Physiology. Anatomy and Physiology questions and answers. 5. Place the events of intramembranous ossification in order (0.5): A. Accumulating osteoid is laid down between embryonic blood vessels in a random manner and mesenchymal cells condense around the bone material to form the periosteum. B.The following are major steps in the process of intramembranous ossification: 1. Trabecular matrix and periosteum form. 2. Secreted osteoid traps osteoblasts, which then become osteocytes. 3. Compact bone develops superficial to the trabecular bone. 4. Mesenchymal cells group into clusters, and ossification centers form.Place the steps of endochondral ossification in the correct order from first to last. A) Osteoblasts build the bone collar on the bone's external surface, bone begins to ossify from the outside, internal cartilage starts to calcify and chondrocytes die B) The chondroblasts in the perichondrium differentiate into osteoblasts C) Cartilage is replaced by bone, the epiphyses finish ossifying D) In ...Osteoblasts secrete extracellular matrix that surrounds them. Calcification: step 2. Matrix stops cells in the lacunae and extend their cytoplasmic processes into cannaliculi that radiate in all directions. Soon calcium and mineral salts are deposited and matrix calcifies and hardens. Formation of trabeculae: step 3. As matrix forms it develops ...Ossification, or osteogenesis, is the process of bone formation by osteoblasts. Ossification is distinct from the process of calcification; whereas calcification takes place during the ossification of bones, it can also occur in other tissues. Ossification begins approximately six weeks after fertilization in an embryo. Before this time, the ...May 18, 2021 · The flat bones of the face, most of the cranial bones, and the clavicles (collarbones) are formed via intramembranous ossification. The process begins when mesenchymal cells in the embryonic skeleton gather together and begin to differentiate into specialized cells (Figure 5.4.1.a 5.4. 1. Step 1. Arrange the steps of endochondral ossification and epiphyseal bone growth in the correct order. There is no time limit and you have unlimited attempts to get them all correct. There is no partial credit, so make sure to think carefully and learn from any mistakes. 1 1 10 1 Below are steps of endochondral ossification and epiphyseal bone ... Citation, DOI, disclosures and article data. Intramembranous ossification describes the process of ossification from mesenchymal cells (stem cells) without a cartilaginous template and is involved in the healing process of fractures. The stages of intramembranous ossification osteogenesis are as follows:When OB are surround by matrix they differentiate into osteocytes. 1. Mesenchyme cells divide into osteoprogenitor cells that further divide into osteoblasts. 5. Lamellar bone replaces trabeculae on the outer surface to become compact bone. 4. Eventually, bone replaces hyaline cartilage all over expect - epiphyseal plates & articular cartilage. 2.Bone Growth. Bones grow in length at the epiphyseal plate by a process that is similar to endochondral ossification. The cartilage in the region of the epiphyseal plate next to the epiphysis continues to grow by mitosis. The chondrocytes, in the region next to the diaphysis, age and degenerate. Osteoblasts move in and ossify the matrix to form ...Step 1. Arrange the steps of endochondral ossification and epiphyseal bone growth in the correct order. There is no time limit and you have unlimited attempts to get them all correct. There is no partial credit, so make sure to think carefully and learn from any mistakes. 1 1 10 1 Below are steps of endochondral ossification and epiphyseal bone ...MGA Thermal co-founders Erich Kisi and Alex Post. Image Credits: MGA Thermal MGA Thermal co-founders Erich Kisi and Alex Post. Image Credits: MGA Thermal MGA Thermal wants to help ...Study with Quizlet and memorize flashcards containing terms like step 1, Step 2, Step 3 and more.Sequence of returns risk can shorten your retirement account's longevity. Learn what sequence risk is and how to plan for it in your portfolio. Calculators Helpful Guides Compare R... step 3. osteoblasts form spongy bone in the space occupied by cartilage. step 4. osteoblasts beneath the periosteum deposit compact bone. step 5. osteoblasts become osteocytes when bony matrix completely surrounds them. step 6. Put the steps of endochondral ossification in the correct order: - blood vessels and differentiating osteoblasts from ... Step 1. Intramembranous ossification is an essential process involved in the formation and remodeling of bon... ( 150 Uncalcified Calcium salts in organic matrix the calcified bone Mesenchymal Osteogenic cells cells Collagen fibers s ecreting Early compact bone Early spongy bone ob Trabeculae alearly organic matrix spongy bone Osteocytes ...Intramembranous ossification. Intramembranous ossification forms flat and irregular bones. In this process, mesenchymal cells differentiate directly into …Anatomy and Physiology questions and answers. ca Place the events in the proper sequence in which they occur during intramembranous ossification. View Available Hint (s) Reset Help 20 0 G @ :0 Osteoblasts form and produce osteoid. Continuous plate of spongy bone forms. Vessels are trapped by the growing spicules.If you use a MacBook to run your business, you should be aware of the proper way to calibrate your MacBook battery. A properly maintained battery ensures that you get the most out ...Anatomy and Physiology. Anatomy and Physiology questions and answers. 5. Place the events of intramembranous ossification in order (0.5): A. Accumulating osteoid is laid down between embryonic blood vessels in a random manner and mesenchymal cells condense around the bone material to form the periosteum. B.Which of the following selections correctly lists the sequence of events that occur during intramembranous ossification? A. calcification B. ossification center develops C. development of new periosteum D. formation of trabeculaeAmniotic band sequence (ABS) is a group of rare birth defects that are thought to occur when strands of the amniotic sac detach and wrap around parts of the baby in the womb. The d...Intramembranous ossification. Intramembranous ossification is the characteristic way in which the flat bones of the skull and the turtle shell are formed. During intramembranous ossification in the skull, neural crest-derived mesenchymal cells proliferate and condense into compact nodules. (Thus, intramembranous ossification is not occurring ...Learning tools, flashcards, and textbook solutions | Quizletsteps of intramembranous ossification. Terms in this set (6) step one. sheets of relatively undifferentiated connective tissue appear at sites of future bones. step two. partially differentiated connective tissue cells collect around blood vessels in …The method for getting Siri to say names the right way has changed in iOS 15. Siri is no one’s favorite virtual assistant, and if it’s also always pronouncing your name wrong, it’s...major steps in bone development: intramembranous ossification (4-6) 4. osteoblasts become osteocytes when bony matrix completely surrounds them. 5. mesenchyme on the surface of each developing structure condenses to form periosteum. 6. osteoblasts on the inside of the periosteum deposit compact bone over the spongy bone.Medicine Matters Sharing successes, challenges and daily happenings in the Department of Medicine ARTICLE: Genome sequencing unveils a regulatory landscape of platelet reactivity A...OpenStaxCollege. Learning Objectives. By the end of this section, you will be able to: Explain the function of cartilage. List the steps of intramembranous ossification. List … The flat bones of the face, most of the cranial bones, and the clavicles (collarbones) are formed via intramembranous ossification. The process begins when mesenchymal cells in the embryonic skeleton gather together and begin to differentiate into specialized cells (Figure 5.5.1.a 5.5. 1. Osteoblasts secrete extracellular matrix that surrounds them. Calcification: step 2. Matrix stops cells in the lacunae and extend their cytoplasmic processes into cannaliculi that radiate in all directions. Soon calcium and mineral salts are deposited and matrix calcifies and hardens. Formation of trabeculae: step 3. As matrix forms it develops ... The steps of intramembranous ossification are shown in Figure 2. Figure 2 Steps of intramembranous ossification: ossification center appears in fibrous connective tissue membrane (A), bone matrix is secreted (B), woven bone and periosteum form (C), bone collar of compact bone forms and marrow appears (D).Correctly order the following key steps in the process of endochondral ossification. 1. Chondrocytes die. 2. Osteoblasts build the bone collar on the external surface of the bone. 3. Perichondrium is invaded by blood vessels. 4. In the primary ossification center, osteoblasts replace calcified cartilage with early spongy bone. 5. Partially. Intramembranous Ossification Correctly sequence the steps of intramembranous ossification. Partially differentiated cells enlarge and differentiate into osteoblasts. Osteoblasts on the inside of the periosteum deposit compact bone over the spongy bone Connective tissue on the surface of each developing structure forms a periosteum ... Answer and Explanation: 1. Most bones in the human body originate from hyaline cartilage in a process known as endochondral ossification. This process, reflected in the development of the femur in figure 1 below, occurs in the following sequence: Chondrocytes in the center of the shaft of cartilage enlarge such that the extracellular matrix is ...The flat bones of the face, most of the cranial bones, and the clavicles (collarbones) are formed via intramembranous ossification. The process begins when mesenchymal cells in the embryonic skeleton gather together and begin to differentiate into specialized cells (Figure 5.5.1.a 5.5. 1.Anatomy and Physiology questions and answers. Endochondral Ossification Correctly sequence the steps of endochondral ossification. Osteoblasts beneath the periosteum deposit a thin layer of compact bone. Cartilage tissue breaks down while the periosteum develops Blood vessels and osteoblasts from the penosteum invade the disintegrating tissue. Step 4. Spicules unite to form trabeculae of spongy bone surrounded by endosteum. Step 5. Remodeling of spongy bone forms compact bone with periosteum around. outer surface. Step 6. Study with Quizlet and memorize flashcards containing terms like Mesenchymal cells differentiate into osteoblast, Osteoblasts secrete matrix, Osteoblasts surrounded ... Nov 21, 2023 · During intramembranous ossification, the mesenchymal tissue transforms directly into a bone. This process occurs primarily in the bone of the skull. The mesenchymal tissue consists of loose cells ... Figure \(\PageIndex{1}\): Intramembranous Ossification. Intramembranous ossification follows four steps. (a) Mesenchymal cells group into clusters, and ossification …Apr 9, 2024 · Intramembranous ossification is a process that forms flat bones such as the skull and the clavicle, through the remodelling of mesenchymal connective tissue. Intramembranous ossification begins in-utero and continues into adolescence. At birth, the skull and clavicles are not completely ossified and the cranial sutures (junctions between the ... Simpler of the two methods of bone formation. The flat bones of the skull, most of the facial bones, mandible, and medial parts of the clavicle are formed in this way. Also, the "soft spots" that help the fetal skull pass through the birth canal later harden as they undergo intramembranous occification. Step 1 - Development of the Ossification ... steps of intramembranous ossification. Terms in this set (6) step one. sheets of relatively undifferentiated connective tissue appear at sites of future bones. step two. “If Africans fail to generate essential data and make such available we'll possibly suffer the same fate as with Rotavirus vaccine.” Pools of genome sequences of SARS-CoV-2 from al...Correctly order the following key steps in the process of endochondral ossification. 1.Chondrocytes die. 2.Osteoblasts build the bone collar on the external surface of the bone. 3.Perichondrium is invaded by blood vessels. 4.In the primary ossification center, osteoblasts replace calcified cartilage with early spongy bone. 5.Perichondrial cells differentiate into osteogenic cells then into ... Partially. Intramembranous Ossification Correctly sequence the steps of intramembranous ossification. Partially differentiated cells enlarge and differentiate into osteoblasts. Osteoblasts on the inside of the periosteum deposit compact bone over the spongy bone Connective tissue on the surface of each developing structure forms a periosteum ... intramembranous ossification — Quiz Information. This is an online quiz called intramembranous ossification. You can use it as intramembranous ossification practice, completely free to play. Currently Most Played. Math Theorems and Constants. The world - Fifteen islands. Famous Hats (part 1)Question: 34) Sequence the following events of intramembranous ossification, ots) (Click and drag to put the items in the correct order, or click here to recorder by entering numbers directly 1 the periosteum is formed from other mesenchymal cells 2 > spongy bone is formed and innervated by blood vessels 3 > begin with the dense fibrous CT template …Steps of bone deposition. ... Which of the following selections correctly lists the sequence of events that occur during intramembranous ossification? Ossification center develops > Calcification > Formation of trabeculae > Development of new …What are the 7 steps of intramembranous ossification in the correct order? Here’s the best way to solve it. Who are the experts? Experts have been vetted by Chegg as specialists in this subject. Expert-verified. 1.mesenchymal cells join together to form future bone. Mesenchymal cells turns into chondroblasts.Jun 18, 2021 · Cell biology. endochondral bone formation occurs with a cartilage model. chondrocytes produce cartilage which is absorbed by osteoclasts. osteoblasts lay down bone on cartilaginous framework (bone replaces cartilage, cartilage is not converted to bone) forms primary trabecular bone. bone deposition occurs on metaphyseal side. Study with Quizlet and memorize flashcards containing terms like Which of the following selections correctly lists the sequence of events that occur during intramembranous ossification? Entry field with correct answer Ossification center develops > Calcification > Formation of trabeculae > Development of new periosteum. Calcification > Ossification center develops > Formation of trabeculae ...Discover the intramembranous ossification steps, the cells involved in the process, and what differentiates intramembranous ossification from endochondral ossification. Updated:...The directional variations in cartilage growth cause shape changes in developing bones and are responsible for the dramatic changes in skeletal appearance during development (Figures 1.9 and 1.10). During endochondral growth and ossification, the chondrocytes undergo a characteristic process of proliferation, maturation, hypertrophy, and death.Aug 30, 2023 · Intramembranous ossification is complete by the end of the adolescent growth spurt, while endochondral ossification lasts into young adulthood. The flat bones of the face, most of the cranial bones, and a good deal of the clavicles (collarbones) are formed via intramembranous ossification, while bones at the base of the skull and the long bones ... Nov 21, 2023 · During intramembranous ossification, the mesenchymal tissue transforms directly into a bone. This process occurs primarily in the bone of the skull. The mesenchymal tissue consists of loose cells ... Steps of intramembranous bone formation. aggregation of undifferentiated mesenchymal cells; osteoblast differentiation; organic matrix depositionChoose the steps of intramembranous ossification in order to accurately reflect the sequence of events. This problem has been solved! You'll get a detailed solution that helps you learn core concepts.Figure 10.4.1. Intramembranous ossification. Intramembranous ossification follows four steps. (a) Mesenchymal cells group into clusters, and ossification centres form. (b) …Steps of intramembranous bone formation. aggregation of undifferentiated mesenchymal cells; osteoblast differentiation; organic matrix depositionIntramembranous ossification is the process of bone development from fibrous membranes. It is involved in the formation of the flat bones of the skull, the mandible, and the clavicles. Ossification begins as mesenchymal cells form a template of the future bone. Osteogenic cells. Osteogenic cells become osteoblast.step 3. osteoblasts form spongy bone in the space occupied by cartilage. step 4. osteoblasts beneath the periosteum deposit compact bone. step 5. osteoblasts become osteocytes when bony matrix completely surrounds them. step 6. Put the steps of endochondral ossification in the correct order: - blood vessels and differentiating osteoblasts from ...Question: Based on their shape, the bones of the Cranium can be classified as what type of bone? flat bones b. long bones c. irregular bones d. short bones Answer: flat bones Question: Functions of the Skeletal System include: Answer: Protects soft tissue Point of attachmentsDuring intramembranous ossification, the undifferentiated mesenchymal cells of the connective tissue like the periosteum become osteogenic cells, such as the osteoblasts, that lead to bone ...Intramembranous ossification is the process by which flat bones are formed. For this process, osteoblasts differentiate directly from mesenchymal cells to form the bone matrix. Long bones are formed by endochondral ossification, which is characterized by the presence of a cartilaginous model in which chondrocytes …correctly sequence the stwps of intramembranous ossification. Osteoblasts on the inside of the periosteum deposit compact bone over the spongy bone. Osteoblasts become osteocytes when bony matrx completely surrounds them.
34) Sequence the following events of intramembranous ossification, ots) (Click and drag to put the items in the correct order, or click here to recorder by entering numbers directly 1 the periosteum is formed from other mesenchymal cells 2 > spongy bone is formed and innervated by blood vessels 3 > begin with the dense fibrous CT template 4 > the primary ossification center froms from a .... Safeway barbur blvd portland
Steps to Intramembranous Ossification. step one. Click the card to flip 👆. flat bones begin when groups of cells differentiate into osteoblasts. Click the card to flip 👆. 1 / 8.Figure 10.4.1. Intramembranous ossification. Intramembranous ossification follows four steps. (a) Mesenchymal cells group into clusters, and ossification centres form. (b) … Study with Quizlet and memorize flashcards containing terms like Place the following images into the correct order to represent the sequence of the steps of fracture healing., Place the following images into the correct order to represent the sequence of the steps of endochondral ossification., Place the following stages into the correct spaces to represent the chronological order of ... Terms in this set (13) Start studying intramembranous and endochondral ossification process. Learn vocabulary, terms, and more with flashcards, games, and other study tools.Step 1. Put the steps of endochondral ossification in the correct order Rank the options below. Cartilage calcifies, and a periosteal bone collar forms. The primary ossification center forms in the diaphysis. Bone replaces cartilage except at the epiphyseal plates. Secondary ossification centers form in the epiphysis The fetal hyaline cartilage ...steps in endochondral bone formation. step one. Click the card to flip 👆. Cartilaginous model made of a connective tissue known as hyaline cartilage grows rapidly and then begins to change. Click the card to flip 👆. 1 / 12.Osteoblasts build the bone collar on the external surface of the bone. 3. Perichondrium is invaded by blood vessels. 4. In the primary ossification center, osteoblasts replace calcified cartilage with early spongy bone. 5. Perichondrial cells differentiate into osteogenic cells then into osteoblasts. 3, 5, 2, 1, 4.Anatomy and Physiology. Anatomy and Physiology questions and answers. 5. Place the events of intramembranous ossification in order (0.5): A. Accumulating osteoid is laid down between embryonic blood vessels in a random manner and mesenchymal cells condense around the bone material to form the periosteum. B.Discover the intramembranous ossification steps, the cells involved in the process, and what differentiates intramembranous ossification from endochondral …When does this happen: spongy bone expands in spicules and blood vessels migrate after spongy bone creation begins? a. Endochondral ossification b. Intramembranous ossification; Bone tissue can only grow by the addition of new bone to existing bone. This is called: (a) interstitial growth. (b) endochondral ossification. (c) intramembranous ...Anatomy and Physiology. Anatomy and Physiology questions and answers. 5. Place the events of intramembranous ossification in order (0.5): A. Accumulating osteoid is laid down between embryonic blood vessels in a random manner and mesenchymal cells condense around the bone material to form the periosteum. B.Correctly order the following key steps in the process of endochondral ossification. 1. Chondrocytes die. 2. Osteoblasts build the bone collar on the external surface of the bone. 3. Perichondrium is invaded by blood vessels. 4. In the primary ossification center, osteoblasts replace calcified cartilage with early spongy bone. 5.Intramembranous ossification is complete by the end of the adolescent growth spurt, while endochondral ossification lasts into young adulthood. The flat bones of the face, most of the cranial bones, and a good deal of the clavicles (collarbones) are formed via intramembranous ossification, while bones at the base of the skull and the …Intramembranous ossification step 1 1.change from osteoprogenitor cells and into osteoblasts 2.osteoblasts secrete the organic extracellular matrix of bone until they are surrounded by it. Step 4. Spicules unite to form trabeculae of spongy bone surrounded by endosteum. Step 5. Remodeling of spongy bone forms compact bone with periosteum around. outer surface. Step 6. Study with Quizlet and memorize flashcards containing terms like Mesenchymal cells differentiate into osteoblast, Osteoblasts secrete matrix, Osteoblasts surrounded ... During intramembranous ossification, compact and spongy bone develops directly from sheets of mesenchymal (undifferentiated) connective tissue. The flat bones of the face, most of the cranial bones, and the clavicles (collarbones) are formed via intramembranous ossification. The process begins when mesenchymal cells in the embryonic skeleton ... Study with Quizlet and memorize flashcards containing terms like Which of the following correctly lists the steps of fracture repair in sequence?, A sternal puncture is often employed to obtain a sample of, The components of the pelvic girdle are called and more.Intramembranous ossification of non-vault bones (e.g., bones of the facial skeleton) is not well described. ... Remodeling of the bony region is the last step in the process. Open in a separate window. Figure 4. Schematic of the cellular zones of distraction osteogenesis. The fibrous interzone (FIZ) forms first and is composed of a variety of ...Endochondral ossification takes much longer than intramembranous ossification. Bones at the base of the skull and long bones form via endochondral ossification. In a long bone, for example, at about 6 to 8 weeks after conception, some of the mesenchymal cells differentiate into chondrocytes (cartilage cells) that form the ….